Elderberry may reduce the effectiveness of immune suppressants, which are common medications for people who have undergone organ transplant procedures. View abstract. In supplement form, elderberry influences blood sugar levels and cholesterol levels. Edible berry extracts like elderberry extract are rich in anthocyanins and have been shown to have a broad spectrum of therapeutic, pharmacologic and anti-carcinogenic properties. Compend.Contin.Educ.Dent. Several studies have found benefits to support the use of elderberry for flu symptoms as well. Taking a specific elderberry extract syrup (Sambucol, Nature's Way) seems to reduce. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. doi:10.1016/j.ctim.2018.12.004, Tiralongo E, Wee SS, Lea RA. Poisoning from elderberry juice. Read our, Natural and Herbal Cold and Flu Treatments. However, some groups of people should avoid elderberry. Dr. Todorov notes that for hundreds of years, herbalists have advocated using elderberry syrups and teas to combat upper respiratory infections. Elderberry contains antioxidants that may help protect your cells from damage . An evidence-based systematic review of elderberry and elderflower (Sambucus nigra) by the Natural Standard Research Collaboration. This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Version: 1.01. The group treated showedsignificant improvement in most signs of flu, whilethe placebo group showed no improvement in symptom severity. Inflammatory cytokines, An evidence-based systematic review of elderberry and elderflower (, Chemical profiling and UHPLC-QToF analysis for the simultaneous determination of anthocyanins and flavonoids in Sambucus berries and authentication and detection of adulteration in elderberry dietary supplements using UHPLC-PDA-MS, 2021 US open forum: elderberry standards development, A 2020 study did not find black elderberry to improve symptoms or reduce the amount of time of illness. There is no significant evidence to support that it may exacerbate the immune system. Elderberries can have serious side effects if the berries are eaten raw. Hashimotos occurs when the body attacks the thyroids hormone-producing cells. If you've thought about taking an elderberry supplement, know that the deep purple berries are packed with desirable nutrients. Phytother Res. For those who understand their condition, or want to be proactive in supporting the thyroid gland, there are many natural supplements to consider. Elderberry Supplementation Reduces Cold Duration and Symptoms in Air-Travellers: A Randomized, Double-Blind Placebo-Controlled Clinical Trial. 2017;72(1):82-7. No supplement is intended to treat, cure, or prevent disease. Clin Chem 1999;45:574-6. Elderberry is available in many different types of products, including syrups and mouth rinses. Elderberries, raw. Barak V, Halperin T, Kalickman I. This article will review the potential uses of elderberry, how to safely use it, and possible concerns with using elderberry. Side effects, in theory, can include cramping, bleeding, early. View abstract. Frank T, Sonntag S, Strass G, Bitsch I, Bitsch R, Netzel M. Urinary pharmacokinetics of cyanidin glycosides in healthy young men following consumption of elderberry juice. Elderberry has not been proven to prevent COVID-19 Some have even relied on elderberry products to help ease the effects of cancer, depression and HIV/AIDS. Is elderberry recommended to prevent COVID-19? The uncertainty surrounding COVID-19 gave birth to much research on its influence outside the respiratory system, with the thyroid gland as a major stakeholder. However, she is careful to take a scientific approach, and doesn't currently endorse the use of elderberry syrup for colds and flu. 2020;35(11):3271-3277. doi:10.1007/s11606-020-06170-w, Hawkins J, Baker C, Cherry L, Dunne E. Black elderberry (Sambucus nigra) supplementation effectively treats upper respiratory symptoms: A meta-analysis of randomized, controlled clinical trials. J Gen Intern Med. However, here are a few key points to keep in mind: Unripe and uncooked elderberries are toxic and may nausea, vomiting, and diarrhea. The gland produces a steady supply of thyroid hormones required for these processes. Traditionally, elderberry has been used topically to treat wounds, as well as taken orally for cold and flu symptoms. Supplements should always be stored out of reach of children and pets to prevent accidental consumption. Elderberry can theoretically exacerbate (worsen) symptoms of an autoimmune disease, as it may stimulate more activity in the immune system. Forster-Waldl E, Marchetti M, Scholl I, Focke M, et al. Discontinue use and contact your physician if you experience . BMC Complement Med Ther. Health benefits of the elder plant include naturally improving: Research published in the Journal of International Medical Research suggests that when its used within the first 48 hours of onset of symptoms, the plant may even help relieve and shorten the duration of cold and flu. Use exactly as directed on the label, or as prescribed by your healthcare provider. You can receive these benefits from taking an elderberry supplement. The syrups usually lack the additional vitamin C and zinc. A cup also contains the . It is not outwardly visible but consists of two lobes found on either side of your windpipe. Ripe, cooked berries from most of theSambucusspeciesare edible. Dietary supplements are not regulated like drugs in the United States, meaning the Food and Drug Administration (FDA) does not approve them for safety and effectiveness before products are marketed. For example, one animal model showed that giving mice with high cholesterol and HDL cholesterol dysfunction anthocyanin-rich black elderberry extract helped reduce hepatic cholesterol levels and improved HDL function. There are also recipes for elderberry-based medications dating back toAncient Egypt. Samuels N, Saffer A, Wexler ID, et al. Although not all side effects are known, elderberry is thought to be possibly safe when taken as directed for a short period of time. Elderberry has antioxidant properties that may be beneficial for balancing blood sugar in diabetes, but current evidence is limited. If you currently take any of the following medications, you should talk to your health care provider before using an elderberry supplement or any other elder plant products: Erythritol is now one of the most popular natural zero-calorie sweeteners available. Research has confirmed thatextracts of elderflower stimulate glucose metabolism and the secretion of insulin, which could potentially help lower blood sugar levels. Our team aims to be not only thorough with its research, but also objective and unbiased. Known as the emmenagogue effect, hibiscus tea and extracts can encourage blood flow to the uterus to help stimulate menstruation. Its most common use cases are for treating cold and flu symptoms and providing COVID relief. Only take the amount recommended on the label. Thank you, {{form.email}}, for signing up. One of the most well-studied elderberry supplement benefits is its powerful immune-boosting properties. It also plays a major role in the growth, development, and functioning of the heart, digestive tract, and muscles. In vitro inhibition of CYP3A4 by the multiherbal commercial product Sambucus Force and its main constituents Echinacea purpurea and Sambucus nigra. The little fruits also contain anthocyanin, a compound that can improve overall skin vitality. Macknin M, Wolski K, Negrey J, Mace S. Elderberry extract outpatient influenza treatment for emergency room patients ages 5 and above: a randomized, double-blind, placebo-controlled trial. Further research is needed. Stop using elderberry and call your doctor at once if you have: severe or ongoing . Since there is no recommended dosage, follow the instructions on the product label or ask your provider how much you should use. Elderberry is most commonly used orally as a syrup. These include the: Unripened, raw elderberries can release cyanide into your body and make you sick. Elderberry suggested uses include for treatment and prevention of the common cold, cough and flu symptoms, sinusitis, as an immunostimulant, and treating mouth ulcers and tonsillitis.Suggested uses for elderberry extract include reducing the damaging effects of LDL cholesterol, and protection as an antioxidant.Suggested uses for elderberry leaves for topical application includes treatment of . This can cause nausea, vomiting, and diarrhea, or more serious side effects if consumed in large quantities. * Elderberry supplements and syrups can be taken daily if they are made by reputable companies. Some don't work well with prescription medicines. View abstract. It may provide relief from the common cold and flu, as well as allergies and sinus infections. Elderberry supplementation reduces cold duration and symptoms in air-travellers: a randomized, double-blind placebo-controlled clinical trial. Suzanne Fisher, RD, founder of Fisher Nutrition Systems, has been a board-certified registered dietitian and licensed nutritionist for over 30 years. Verywell Health's content is for informational and educational purposes only. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Intense stress can also affect your period. J.Clin.Dent. Elderberry tea is another great option, especially if you use elderberry for flu and cold symptoms. Anti-Inflammatory Diets May Improve Fertility, Exercise May Be an Anti-COVID Secret Weapon, Dr. Whyte's Book: Take Control of Your Diabetes Risk, Street Medicine Reaches People Where They Live, Health News and Information, Delivered to Your Inbox, Chronic obstructive pulmonary disease (COPD), Flu (influenza). Elderberry should not be used in place of medication prescribed for you by your doctor. Even ripe berries can contain trace amounts, so elderberries must be cooked before you eat them. View abstract. Common side effects may include: nausea, vomiting; stomach cramps; Elderberry and Thyroid: Is It Safe for Autoimmune Disease? If you have a preexisting thyroid condition, its best to speak with a doctor before adding elderberry into your treatment regimen. Elderberry has made its wayinto cosmetic products, and for good reason. In addition, stay alert for potential elderberry side effects. Does elderberry interact with medications? One study published in theJournal of Medicinal Foodcompared theanticancer properties of European and American elderberry fruits. Taking an elderberry supplement regularly can optimize your immune system support. If you decide to make your own elderberry syrup or similar product, obtain instructions from a reputable source and follow the directions exactly. Exp Pathol Health Sci. You may report side effects to FDA at 1-800-FDA-1088. J Funct Foods. 2014;11(1):80-120. doi:10.3109/19390211.2013.859852. Sambucus nigrais the full scientific name of the most common variety used for medicinal purposes, as well as the species on which themajority of scientific research has been conducted. Iran J Pharm Res. 2017;31(4):533-554. doi:10.1002/ptr.5782, Wieland LS, Piechotta V, Feinberg T, et al. 2020 Sep 14. doi: 10.1007/s11606-020-06170-w. View abstract. Additionally, research has shown vitamin C to be effective against the thyroid antibodies in Hashimotos disease. J Altern Complement Med 1995;1:361-9. Divinity Nutra does not provide medical advice, diagnosis, or treatment recommendations. Furthermore, a 2017 animal study published in theInternational Journal of Molecular Sciences noted that elderberries can serve as a potential source of bioactive compounds for formulations used for the management of diabetes. Do not give any herbal/health supplement to a child without medical advice. J Int Med Res 2004;32:132-40. Yet, one of its key findings was the stimulation of pro-inflammatory cytokines after elderberry consumption. The Poison Plant Patch, Novia Scotia Museum, 2007. Both elderberry flowers and fruits are used to help reduce cold and flu symptoms. 2016 Mar 24;8(4). In traditional or folk medicine, the elder plant was used as a laxative to relieve constipation. It has a long history of use for, Elderberry fruit extracts have most often been used by adults in doses up to 1200 mg by mouth daily for 2 weeks. What are the benefits of elderberry? In a 2019 study on elderberry for cold and flu, elderberry appeared to reduce the duration of upper airway symptoms caused by the flu when taken at the onset of symptoms. Research suggests elderberry juice syrup may help reduce the severity and duration of symptoms associated with colds and flu. 2022;110. The berries are used to make medicine. If desired, you may mix elderberry liquid with water, fruit juice, yogurt, or a smoothie. This positive development leads to better overall health. https://medlineplus.gov/autoimmunediseases.html, http://www.thyroid.org/hashimotos-thyroiditis/, https://pubmed.ncbi.nlm.nih.gov/11399518/, https://www.sciencedirect.com/science/article/abs/pii/S1756464619300313, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372600/, 6 Health Benefits and Uses for Elderberry Supplements. Elderberry may cause serious side effects. This information may not fit your specific health circumstances. Some researchers have suggested that the syrup shortens the duration of some illnesses and makes them less severe; however, the study findings have varied. Look for supplements with a USP, NSF, or ConsumerLab label indicating they can be trusted to contain the listed ingredients. Right below the center of your throat lies a butterfly-shaped organ called the thyroid gland. Stop using elderberry and call your doctor at once if you have: severe weakness, dizziness, or confusion. 2007 Oct;29(8):525-33. But it may cause: Get medical attention if you develop these symptoms after consuming elderberry. Unfortunately, direct research examining Hashimotos disease is limited. Read more: 8 Foods That Boost Your Immune System. The elder plant may possess beneficial anti-inflammatory, antiviral, and anti-cancer effects, according to the University of Maryland Medical Center. It may also help lower blood sugar, improve heart health, support healthy skin and act as a. Immunosuppressants are also used for other conditions, and common ones include: Keep elderberry in a cool, dry place. For example, several forms are marketed for immune support, and they also contain vitamin C, zinc, vitamin A, or vitamin E. This is especially important with elderberry products. A recent systematic review found that elderberry may be a safe option for reducing the severity and duration of respiratory infections like the common cold and flu. As with all supplements, it is important to look for products that have been third-party tested. Try adding lemon, cinnamon or mint to give the flavor and health benefits a hearty boost. Elderberry has many nutrients. We comply with the HONcode standard for trustworthy health information. Elderberry is a berry from a European or Black elder tree. This can cause nausea, vomiting, and diarrhea, or more serious side effects if consumed in large quantities. Some research suggests that elderberry tea benefits constipation and can help support regularity and digestive health. Elderberry can increase the activity of the immune system. The findings were further supported by a 2019 study that was observing the anti-influenza properties of elderberries. 2016;8(2):59-66. The elderberry side effects are limited, rare, and often mild. Ripe, cooked elderberry fruit is considered safe to eat in moderation. Looking for a natural remedy that has a long history of medicinal use? However, elderberry extract in supplement form is generally safe to take in small doses. In some clinical trials, adults took 3 teaspoons (1 tablespoon) of elderberry extract in syrup form four times daily for five days. Bioactive properties ofSambucus nigraL. as a functional ingredient for food and pharmaceutical industry. Wondering where to buy elderberry and how to start adding it to your diet? Hashimotos thyroiditis and other autoimmune diseases are serious conditions and must be handled with care. The information in our articles is NOT intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice. Increased fiber consumption has been shown to improve your gastrointestinal system function. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182. However, there is not enough evidence to support these claims. Speak with a, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, 6 Minutes of Exercise May Protect Brain From Alzheimer's, 'Disturbing' Rate of Adverse Events During Hospital Stays. Another popular way to consume elderberries is to purchase an elderberry syrup. Does it really work? In rare cases, they can completely block your periods. Mynarczyk K, Walkowiak-Tomczak D, ysiak GP. Large quantities of the toxin may cause serious illness. If you have an autoimmune disease, such as rheumatoid arthritis, ask your doctor before taking elderberry supplements because it may stimulate the immune system. Cyanogenic glycoside analysis in American elderberry. American elderberry ( Sambucus canadensis ) is more shrub-like and can grow up to 8 to 10 feet high, while European black elder ( Sambucus nigra) has the makings of a small tree and will reach 20 feet. Side effects are rarely reported and are very mild and manageable. Elderberry may also be used for purposes not listed in this product guide. Complement Ther Med. View abstract. The effect of Sambucol, a black elderberry-based, natural product, on the production of human cytokines: I. However, it does not prevent infections or illnesses. Its never safe to eat unknown berries in nature, as they may have dangerous effects. If your doctor gives you the "all clear" to take elderberry along with an existing medication, ensure that you follow the dosage instructions to the letter. You can buy dried berries online and in health food stores. What Is the Difference Between Wolfberries & Goji Berries? Jennifer Lefton, MS, RD/N-AP, CNSC, FAND is a Registered Dietitian/Nutritionist and writer with over 20 years of experience in clinical nutrition. J Am Dent.Assoc. No author. A 2016 study published in Nutrients showed that elderberry supplementation was able to reduce cold duration and symptoms in people using air travel. Compared to other types of berries, elderberry is the clear winner. MMWR 1984;33:173-4. If you have eaten an unknown berry and develop concerning symptoms, get immediate medical attention. The multiherbal commercial product Sambucus Force and its main constituents Echinacea purpurea and Sambucus )... Force and its main constituents Echinacea purpurea and Sambucus nigra considered safe to eat unknown berries in,... That the deep purple berries are packed with desirable nutrients no improvement in most signs flu. The effect of Sambucol, Nature 's Way ) seems to reduce cold and. 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Standard research Collaboration unfortunately, direct research examining hashimotos disease and zinc powerful immune-boosting properties cooked before eat! Honcode Standard for trustworthy health information these include the: Unripened, elderberries... And how to start adding it to your diet the potential uses of and...